How Gut Health Impacts Fertility: The Microbiome Connection
- Ellen Kessling
- May 7
- 3 min read

Emerging research is showing the crucial role gut health plays in fertility.
The gut microbiome is a diverse community of bacteria, fungi, and other microorganisms which affect hormone regulation, inflammation, and nutrient absorption in the body, all of which influence reproductive health.
This article explores the link between gut health and fertility and provides practical strategies for maintaining a balanced microbiome.
1. The Gut Microbiome and Hormonal Balance
Hormones such as oestrogen, progesterone, and testosterone are vital for reproductive function. The gut microbiome plays a key role in metabolising and regulating these hormones, particularly through the estrobolome, a group of gut bacteria that influence oestrogen levels.
Imbalances in the gut microbiome (dysbiosis) can lead to disrupted hormone levels, potentially affecting menstrual cycles, ovulation, and sperm quality.
2. Inflammation and Fertility Challenges
Chronic inflammation is linked to conditions such as polycystic ovary syndrome (PCOS) and endometriosis, both of which can impair fertility. An unhealthy gut microbiome can promote systemic inflammation, exacerbating these reproductive disorders.
Consuming anti-inflammatory foods and maintaining gut balance through probiotics and fibre may help reduce inflammation and improve fertility outcomes.
3. Nutrient Absorption for Optimal Reproductive Health
Key nutrients such as folate, zinc, omega-3 fatty acids, and antioxidants are essential for fertility, but poor gut health can impair their absorption of these nutrients in the body.
A diverse and balanced microbiome enhances digestion and nutrient uptake, ensuring that the body receives the necessary vitamins and minerals to support reproductive function in both men and women.
4. The Gut-Vaginal Axis and Sperm Health
The gut microbiome influences the vaginal microbiome, which is essential for preventing infections and maintaining a healthy reproductive environment.
Dysbiosis in the gut can lead to an overgrowth of harmful bacteria in the vaginal tract, increasing the risk of bacterial vaginosis and yeast infections—both of which can negatively impact fertility.
Research also suggests that gut health affects sperm motility, morphology, and DNA integrity, highlighting its importance for male fertility as well.
How to Support a Fertility-Boosting Gut Microbiome
Optimising gut health can enhance fertility in several ways. Here are some ways you can look after your gut health for optimal fertility:
Increase Prebiotic Intake: Foods such as garlic, onions, leeks, bananas, and asparagus feed your beneficial gut bacteria.
Incorporate Probiotics: Fermented foods like yoghurt, kefir, sauerkraut, and kimchi can introduce beneficial microbes.
Eat Fibre-Rich Foods: Whole grains, legumes, fruits, and vegetables support digestive health and microbiome diversity.
Limit Processed Foods and Sugar: Excess sugar and ultra-processed foods fuel harmful bacteria and can potentially lead to inflammation.
Manage Stress: Chronic stress negatively impacts gut bacteria. Mindfulness, exercise, and quality sleep is so important to support gut health.
In Summary
The gut microbiome plays a fundamental role in fertility by regulating hormones, controlling inflammation, and enhancing nutrient absorption.
Taking proactive steps to support gut health through diet and lifestyle modifications can positively impact reproductive health for both men and women.
If you are experiencing fertility challenges, working with a dietitian or healthcare professional to assess and improve your gut health may be beneficial.
References
Franasiak, J. M., & Scott, R. T. (2017). Reproductive tract microbiome in assisted reproductive technology. Fertility and Sterility, 108(5), 719-727.
Szymanski, L. A., & Lustgarten, J. L. (2020). The estrobolome and its role in reproductive health. Trends in Endocrinology & Metabolism, 31(7), 506-515.
Torres, P. J., et al. (2018). Gut microbiome and polycystic ovary syndrome: A review of current knowledge. Reproductive Sciences, 25(10), 1570-1580.
Foster, J. A., et al. (2017). Gut-brain axis: How the microbiome influences anxiety and depression. Trends in Neurosciences, 40(3), 145-157.
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